The Library provide website evidence for key issues contained in my blogs. The evidence is key research reports. Click on the website URL for your mental exercise. Many reports are abstract only. I will continue to add additional research reports as appropriate.
|REF #, DATE – AUTHOR||ISSUE||ARTICLE LINK|
|Ref. #1 – Mar, 1991 – |
Braak & Braak
|Staging Neuron Damage||https://www.ncbi.nlm.nih.gov/pubmed/1759558|
|Ref. #2 – July 1996 –|
|Quantifying neuon damage||https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6578866/|
|Ref. #3 – Jan 2011 –|
TE Golde et. al.
|Shift to Presymptomatic AD||https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058906/|
|Ref. # 4 – Aug. 2016 – |
Reisa A. Sperling et. al.
|Prevent Amyloid Aggregation||https://projectreporter.nih.gov/project_info_description.cfm?aid=9194290|
|Ref. #5 – Jan. 2018 Rand Rpt.|
Jakub P. Hlavka et. al.
|Future Dementia staff shortages||https://www.rand.org/pubs/research_reports/RR2503.html|
|Ref. #6 – Feb. 2018 FDA||Presymptomatic Guidance||https://www.fda.gov/media/110903/download|
|Ref. #7 – April 2018 – NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease. Clifford R Jack Jr. et. al.||Biological Biomarmers Framework for Presymptomatic AD||https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958625/|
|Ref. #8 – Mar, 2003 |
Tangles and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s Disease.
Gamakopoulos P et.al.
|https://www.alzforum.org/news/research-news/can-apoe-mutation-halt-alzheimers-diseaseAmyloidvolume has no additional preictive value , in terms of clincopathlogic correlations, beyond its interaction with Neurofibrilary tangles (NFT)||https://www.ncbi.nlm.nih.gov/pubmed/12743238|
|Ref. #9: – Nov. 2019 –> esistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report. Arboleda-Velasquez JF et. al.||Alzforum”s –> Can an ApoE Mutation Halt Alzheimer’s Disease?||https://www.alzforum.org/news/research-news/can-apoe-mutation-halt-alzheimers-disease|
|Ref. #10 Feb. 2020 How Much Amyloid Will Kick Off Tangles, and Decline?|
|Amyloid Plaque proceeds Tau Fibrils and Tangles||https://www.alzforum.org/news/conference-coverage/how-much-amyloid-will-kick-tangles-and-decline|